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This study restricted enrolment to the tumour necrosis factor α inhibitor/biologically naïve population on background MTX, thus limiting the ability to extrapolate efficacy and safety to biologically experienced subjects or to assess the safety of baricitinib with other background DMARDs commonly combined in RA treatment.
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Thus, we harvested tissues when all individuals were biologically experiencing the same clinical signs of chytridiomycosis, rather than choosing a fixed time point when individuals vary in disease progression.
In terms of the amount of ups and downs involved, we found them similar to those which our friends experienced biologically.
Within this framework, drive is conceptualized as biologically based and experienced as spontaneous interest typically through genital tingling, sexual thoughts or fantasies, and increased sexual interest in others nearby.
Although all these harmonic stimuli are present in the human auditory environment, the vocalizations of other humans are presumably the most biologically relevant and frequently experienced.
Indeed Kovacs & Devlin [ 17] suggested that children may be biologically 'prepared' to experience symptoms of anxiety rather than depression.
Any biologically required sequence experiences evolutionary pressure (in this case purifying selection) resulting in a narrowing of the range of allowable sequence mutations.
Although self-help and self-guided treatments for PCa-linked depression are to be commended, they will be of relatively little efficacy with men who are anhedonic, and who are therefore biologically incapable of experiencing pleasure, either from behaviourally-induced activities or within the therapeutic bond of psychotherapy.
The clear implication of the study was that political defeat is a biologically stressful experience.
Dr Josine Verhoeven said the cells of people who were severely depressed or who had suffered severe depression appeared biologically older than people who had not experienced depression.
In this scenario, current background POPs serum concentrations could be even more biologically active than were the higher serum concentrations typically experienced before many POPs were banned.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com