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In the breast cancer clinic, there are currently two biologically directed therapies that target either the ER or HER2 proteins.
While the uninformed initialization scheme described above works generally well (Section 3), several reasons may lead researchers to prefer biologically directed solutions.
17 18 Similarly, in biologically directed treatments, such as for cancer treatments, it is possible that a treatment will be effective in one subgroup and ineffective in another.
In the past years, several studies further investigated the prediction of response to therapy and biologically directed class discovery using GEP in leukaemia.
For these reasons, as we demonstrate in Section 3, it is beneficial to have the ability to use different biologically directed and undirected settings, exploring the space of possible solutions.
It is also important that researchers obtain material from sequential samples (with parallel outcome data), taken before and during treatment with conventional therapies, and from biologically directed innovative trials of targeted therapies.
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It is likely that in a dying tissue, most degradation is initially biologically mediated and directed towards specific classes of transcripts, but as the cellular environment continues to deteriorate, the relative importance of stochastic degradation may increase such that at later time-points degradation becomes increasingly uncoupled from biological function.
S-IgA contains antibodies directed to biologically active antigens such as viruses, bacteria, enterotoxins, and enzymes normally restricted to the intestinal tract.
Taken together, these results demonstrate that the capsule and O-antigen form a biologically significant barrier against antibodies directed against non-capsular and O-antigen epitopes.
We removed elevation, as it was correlated with canopy cover and fruit density, which are biologically more direct predictors of bear use.
The diagonal edges are not to be interpreted biologically as direct causal relations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com