Sentence examples for biologically deleterious from inspiring English sources

This likely reflects selection against frameshifting indels becoming common, as they are more often biologically deleterious than inframe mutations.

Taken together, these findings suggest a biologically deleterious effect of heavy alcohol administration on disease progression in SIV-infected primates.

Conversely, IHC can detect epigenetic loss of function events such as methylation that may be as biologically deleterious as homozygous nonsense mutations.

For binding, there is a greater conundrum in that while the real biological decoys are not known, a random contacts model has the potential to be too restrictive in selecting against binding interactions that are not biologically deleterious.

Biologically if deleterious mutation accumulates, the viability of sub-fittest class increases, these results in the single click time longer.

Most of the mutations will be deleterious.

Prominent in this induction process are the cluster of genes that encode proteins involved in limiting both endogenous and exogenous chemicals from initiating deleterious biological effects by directing their metabolism, an event that biologically inactivates the agents and in many cases, facilitates their excretion from the body.

Previous research has shown that compensatory mutations, in which some mutations are conditionally beneficial only in the presence of certain otherwise deleterious mutations, are biologically important [ 32- 34].

These reactive species exert deleterious effects by oxidizing biologically essential molecules and induced oxidative damage of cellular membranes, tissues, and enzymes, which may lead to several diseases [ 4, 8].

Detecting deletions deleterious to a mouse may be biologically viable, and examples of somatic variants, in the tissue sampled given that gene's developmental stage-specific or tissue-specific expression.

Low levels of biologically active testosterone in the aging male may be deleterious to the brain.