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It may be surmised that patients presenting after a shorter duration of symptoms may be harboring more virulent and biologically aggressive forms of cancers when compared to patients with symptoms of longer duration.
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High-grade astrocytomas [anaplastic astrocytoma and glioblastoma (GBM)] are the most biologically aggressive form of cancer and a leading cause of cancer-related mortality and/or morbidity in the pediatric years [ 15, 19, 22].
Uterine serous papillary carcinoma (USPC) is a biologically aggressive variant of endometrial cancer.
Unfortunately, there are currently no efficacious biologically-based treatments for these more aggressive forms of breast cancer whose survival rates are less than 26%.
Glioblastoma Multiforme (GBM) is one of the most aggressive forms of all cancers.
Melanoma is οne of the most aggressive forms of skin cancer.
HER2+ breast cancer is one of the most aggressive forms of breast cancer.
EZH2 expression was elevated in aggressive forms of PCa [ 31].
Conversely, Multigner et al. (2010) estimated stronger associations of serum concentrations of the OC insecticide chlordecone with highly aggressive forms of prostate cancer compared with less aggressive forms.
These findings may assist improved biomarker identification of aggressive forms of colorectal adenocarcinoma.
Inflammatory breast cancer (IBC) is one of the most aggressive forms of breast cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com