In this paper, a feature-based bio-CAD modeling of three-dimensional tissue scaffolds by considering spatial distribution of biologically active materials is presented for biomanufacturing and tissue engineering applications.
In conclusion, even though the fate of the nursing infant in terms of the biologically active materials such as stem cells and miRNAs is not entirely understood, current knowledge indicates that these materials can invade the tissue of the infant, especially in the early developmental period [ 7].
Microencapsulation is a process by which the biologically active materials are enclosed within micro-spherical and semi-permeable containers of 0.2 3.0 mm in diameter (Paredes Juarez et al. 2014; Al-Rammah 2014; Azadi et al. 2016).
This concept is, moreover, valuable not only for technological progress but also for fundamental studies on proteins and other biologically active materials.
This has been partly associated with the different modalities of biomaterials use in therapies, especially with more biologically active materials used as scaffolds in tissue engineering and the type of prolonged extracorporeal contact that is seen with hemodialysis.
Such information emphasizes the impediments that biologically active materials must overcome for absorption across these mucosal surfaces and provides a template for strategies to overcome these barriers for the successful delivery of nano-scale bioactive materials, also known as nano-medicines.
Anti-cancer treatments using biologically active materials, including bioactive peptides, have recently been identified with potent anti-cancer activity and lack of side effects [ 11- 13].
These findings provide insight into the cellular responses of excitable cells to the chemical details of a surface and, thus, may help direct the rational design of biologically active materials.
Recently, the kinetics of molecular intercalation in various layered materials (for example graphene, MoS2, VS2) have been studied using such models, and attention is being focused on understanding the intercalation of biologically active materials into layered double hydroxide hosts (LDHs).
