In comparison to other berries, Aronia contains high amounts of biologically active hydroxycinnamic acids, chlorogenic acid (35.5 mg/100 g) and neochlorogenic acid (21.5 mg/100 g) [ 28].
Fatty acids especially long chain polyunsaturated fatty acids (LCPUFAs) are biologically active fatty acids which have been found to be associated with a number of developmental and functional aspects of the placenta.
Long chain polyunsaturated fatty acids (LCPUFAs) are biologically active fatty acids which regulate placental angiogenesis, inflammation, and oxidative stress.
Finally, CYP2C8 was found involved in the metabolism of arachidonic acid to biologically active epoxyeicosetrenoic acids (EETs) in the kidney.
These authors identified a dietary requirement of trout for α-linolenic acid (LNA, 18 3n-3), however it has since become recognised that the value of LNA as an EFA for trout and Atlantic salmon exists only because these species have the ability to desaturate and elongate LNA to more biologically active fatty acids such as EPA and DHA [ 3, 6, 7].
Lipoxygenases are a family of calcium-dependent dioxygenases, including 5-lipoxygenase (5-LOX), 12-lipoxygenase (12-LOX), and 15-lipoxygenase (15-LOX), that metabolize arachidonic acid to distinct biologically active fatty acid hydroperoxides, such as leukotrienes and hydroyeicosateraenoic acids [20].
Beside an increased energy harvest from the diet, further mechanisms linking gut microbiota to obesity have been subsequently proposed, including chronic low-grade endotoxinemia, regulation of tissutal biologically active fatty acid composition and modulation of gut-derived peptide secretion.
We assume that BRD4770 is converted to BRD9539 in cells since methyl esters of biologically active carboxylic acids are rapidly hydrolyzed in cells and often used as cell-active "pro-drugs" of the less cell-permeable carboxylic acids.
Oriňák et al. [12] applied TLC-SERS technique to the analysis of hydrophobic diterpenoic acids, but the SERS spectra of the three biologically active diterpenes (gibberellic acid, abietic acid, and kaurenoic acid) showed weak and unsatisfactory Raman signals.
They act as endothelium-dependent hyperpolarizing factors (EDHFs) in the renal microcirculation by activating the BK channel in VSMCs and are hydrolyzed by sEH in vivo to less biologically active dihydroxyeicosatrienoic acids (DHETs).
