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The design, synthesis, photoisomerism and biological testing of two peptide-based photoswitchable inhibitors of α-chymotrypsin are presented.
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The biological testing of target compounds showed five promising active compounds 7c, 7d, 7f, 9e and 9f with micromolar DNA-PK activity range from 0.25 to 5 µM.
We present the essential elements of the Synthetic Biology Software Suite (SynBioSS) and discuss the experimental construction and testing of two synthetic biological devices as guided by SynBioSS.
To further assess PSIKO, we also subjected it to the test of two biological datasets, one of which is an oilseed rape dataset that was originally studied in Harper et al. (2012) and the other is from the HapMap 3 project (see Materials and Methods for a brief description of each).
Two models were employed to predict the biological activities of two test sets.
We tested the biological function of two of the predicted CLE signaling peptides in the legume Medicago truncatula.
We therefore used cell-based receptor assays to test the biological activity of two of the purified secreted Fc-fusion proteins.
The biological test was repeated three times.
Proteins were considered to be differentially expressed if they showed at least a two-fold difference between the 0 and 5 d gels at p < 0.05 in t-tests of three biological replicates.
"Seeking to find purity of blood through biological testing evokes the worst memories of World War II.
When a patient escapes from a biological testing facility, carrying with him a strain of super-flu that destroys a majority of the population, two surviving leaders emerge.
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