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The volumetric mass transfer coefficient kLa was determined using a reliable biological test system for stirred vessels up to 3 me (equipped with Rushton turbines or Intermig stirrers).
For each of these inherited disorders, a genetically defined mouse mutant can help identify the key molecular defects in excitability and plasticity in the developing epileptic brain, uncover new molecular targets for therapy, and serve as a reproducible biological test system for experimental strategies to prevent or reverse the onset of seizures.
In order to look into the combined effects of Cd and BDE-209 in vitro, this study was aimed at examining cytotoxic and genotoxic effects using the human colon carcinoma cell line (SW 480) as a biological test system as well as to determine if ROS production was one of the possible mechanisms of their mixture action.
In order to develop an in vitro photosensitization assay, irradiation conditions compatible with the envisaged biological test system should first be determined.
While surface chemistry appeared to have the most drastic influence on AuNPs' behavior in our biological test system, the data could also be interpreted to suggest that AuNP behavior is modulated by core size.
It seems, therefore, that the fundamental principles of IA, the statistical concept of independent random events, cannot be translated fully to our biological test system with multi-component mixtures.
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This process involves the design of robust but sensitive biological test systems and the statistical sifting of biological signals from noise.
Recently, Kase et al. [56] published an extensive literature review survey aiming to give an overview and an evaluation on available and validated biological test systems for the detection of endocrine disruptive and reproductive effects in aquatic systems for monitoring purposes.
In common with various protein growth factors, it displays angiogenic activity in a variety of biological test systems.
In biological test systems results always vary to some extent so that one may sometimes have a favorable result and sometimes not.
The biological test systems include bronchial (Calu-3, 16HBE14o-, BEAS-2B) alveolarolar epithelial (A549) cell lines, mostly from tumors as well as human primary cells isolated from different regions of the respiratory tract [ 22– 25].
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