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These biological terms were also present among the most significantly enriched terms reported by singular enrichment analysis (Additional file 2).
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Functional enrichment analyses of GO biological process terms were also performed for the complete list of mediators, showing metabolic related terms, immune response and inflammatory processes, and cell surface receptor signaling pathways.
The molecular function and biological process Gene Ontology terms are also consistent with the similar results reported in other studies that used needles for EST or transcriptome sequencing [ 6, 23, 24, 26].
For miR156 certain biological terms were found enriched.
The predicted GO terms are also more specific, yielding deeper biological insight into the role of the TF.
But the short term is also encouraging.
Relative and absolute abundance of the most represented GO terms per biological category were also comparable between AB and OV (fig. 1).
Terms of "Biological Process" category were also found to be an over-represented, including translation, intracellular protein transport, signal transduction, small GTPase mediated signal transduction, protein transport, protein modification process, and anti-apoptosis.
In the down-regulated DEGs, the mostly represented GO term of biological process was also "Response to stimulus", followed by "Lipid biosynthetic process", "Organic acid biosynthetic process" and "Lipid localization".
From the GO biological process term percentage distribution, it can be seen that GO terms related with cell proliferation and biological adhesion are also highlighted, although their term numbers are less than those of the others.
Terms from the biological process ontology considered uninformative were also eliminated.
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