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It also provides general insights on how biological systems that require incessant functional changes such as host-defense systems can employ gene families to achieve this goal.
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In consequence, future udder health campaigns should not only consider major differences between housing systems when issuing prevention recommendations but ideally have to consider each farm as an individual biological system that requires specific measures to control a mastitis problem.
The intricate interrelationship between the central and peripheral clocks is a highly regulated system that requires precise specificity to maintain proper biological rhythms.
Constructing novel biological systems that function in a robust and predictable manner requires better methods for discovering new functional molecules and for optimizing their assembly in novel biological contexts.
One obvious avenue is by stimulating biological systems that keep us awake.
Infectious disease is a systems problem that requires systems solutions.
And only one laboratory at MIT will use a biological agent that requires security.
Indeed, standard investigations of biological systems usually rely on computational methods that require the execution of a large number of simulations, such as parameter sweep analysis [ 3], sensitivity analysis [ 4], structure and parameter identifiability [ 5], parameter estimation [ 6– 8], and reverse engineering of model topologies [ 9– 13].
Studies of the biological mechanisms of memory function utilize behavioral tasks that require use of memory systems for successful performance [1].
The overall aim of nanotechnology in biological systems then is to hierarchically assemble molecules into objects and vice versa, using bonds that require low energy consumption.
It is well-known that compartimentalization, in biological systems, naturally require the existence of mechanisms that would keep some key state variables relatively constant, or within bounds, for normal operation of the metabolic processes.
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