Also, Fusi et al. [16] has argued that bistability based on biochemical positive feedback is unlikely to suffice for biological memory storage.
I suggest that even without such cascades of states, bistability based on reinforcement of strengthened synapses by ongoing, "background" neuronal activity could sustain biological memory storage.
The dynamics illustrated in Figs. 5 and 7 do not yet represent a satisfactory system for biological memory storage, because those dynamics have no mechanism for reversing L-LTP and forgetting memories.
Therefore, for networks in which synapses are generally comprised of multiple individual contacts, the argument of Fusi et al. [16] may not suffice to rule out bistability mediated by SRR as a viable biological memory storage mechanism.
Broad investigations of different biological specimens, storage media, storage duration and microbial detection tools are needed to validate these findings.
Biological information storage events are often rapid transitions between discrete states.
The Q & A approach taken in this review lists a series of arguments in a stepwise manner to make the reader wonder why it is only a rather recent process that the concept of the sugar code has taken root in deciphering the mechanistic versatility of biological information storage and transfer.
Therefore, metal nanowires have received immense research intention in recent years owing to their tunable optical and electronic properties and potential applications in nanoelectronic, probes, biological sensors, storage media and sensing devices [9].
