Sentence examples for biological reference values for from inspiring English sources
The proposed biological reference values for MP and EP metabolites are based on the available models for malathion and chlorpyrifos.
It is to be noted that the present study proposes biological reference values for non-specific metabolites of OP pesticides measured in urine.
The slightly higher biological reference values for azinphos-methyl despite a slightly lower NOEL are related to variations in the toxicokinetics of the two substances.
The proposed oral and dermal biological reference values for MP and EP excretions can be used to help interpret biomonitoring data in other populations where nighttime cumulative urinary excretions are collected.
Conversely, the proposal of biological reference values for non-specific OP metabolites rather than specific metabolites appears more accurate for environmental risk assessment of OP exposure where the pesticides to which subjects are exposed are unknown.
From a published no-observed effect level dose for malathion and chlorpyrifos, the model predicts corresponding oral biological reference values for methylphosphate and ethylphosphate derivatives of 106 and 52 nmol/kg of body weight, respectively, in 12-h nighttime urine collections, and dermal biological reference values of 40 and 32 nmol/kg of body weight.
These models were used to predict cumulative urinary amounts of OP metabolites resulting from an exposure to a no-observed effect level (NOEL) dose, which were proposed as biological reference values (BRVs) for prevention in occupational health.
The current paper proposes biological reference values to help interpret biomonitoring data related to an exposure to organophosphorus pesticides in children for which measurements of alkylphosphate metabolites are available.
Inherent biological variations are known to create difficulties in determining the reference values for biological samples in clinical laboratories [76].
As we did for the core oscillator model, we can use non-dimensional parameter values, reference values for length and time, and available biological measurements to calculate values for the dimensional parameters in the signalling model.
Because biological data are instrument-dependent and because technology has evolved over the last two decades, the published capillary blood reference values for blood gases, lactate, ionized calcium (iCa) and glucose may not reflect the present day situation.
