Exact(10)
Without biological proof — a positive blood test or the telltale skin rash — the symptoms are vague and varied and could apply to many conditions.
Obviously, everyone has a brain, ergo, neuroscientific findings apply to everyone, therefore are "newsworthy" (see the "Brain as biological proof" category, above).
They say this is "biological proof" that pollution can harm the heart.
Hence we undertook an effort to design both inhibitors and activators using structure-based drug design techniques and report here the biological proof of concept.
He calls finding this kind of strong biological proof phase zero a necessary step before the expensive Phase I, II and III gamut of clinical trials all medicines must run and demands it of new Sanofi products.
In an interview with NBC's Savannah Guthrie on Tuesday, Dolezal said: "There's no biological proof that Larry and Ruthanne are my parents".
Similar(49)
Our plan for achieving this aim was to: (i) obtain in vitro and in vivo biological proof-of-principle data with a large and commercially available polyamidoamine (PAMAM) dendrimer that we could glycosylate; (ii) identify and make a novel, much smaller and simpler glycosylated dendrimer that had better in vitro and in vivo bioactivity over a longer period of time.
Reed invoked the existence of a biological clock as proof that women could not venture too far from their traditional roles.
We could, however, not dispose of patient's biological samples to proof this hypothesis.
One candidate drug class to prevent organ dysfunction in at-risk patients are statins, for which biological plausibility and proof of concept data exist for salutary effects on infection-related inflammatory response [ 12, 13].
In the present review we discuss both knowledge on the regulatory mechanisms of microRNAs obtained from other biological models and proof of concepts already performed on CHO cells, thus providing an outlook of potential applications of microRNA engineering in production cell lines.
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