MiRNAs are evolutionary conserved and exhibit tissue-specific as well as developmental stage-specific expression [14], [15], suggesting important function in a variety of biological programs, including cell death, neuronal differentiation, synaptogenesis and other developmental processes [16], [17].
Genes from this family participate in various biological processes including developmental programs, defence, and biotic and abiotic stress responses [ 59, 60].
Cellular interactions with extracellular matrices (ECM) through the application of mechanical forces mediate numerous biological processes including developmental morphogenesis, wound healing and cancer metastasis.
miRNAs have been reported to be involved in many biological processes, including developmental timing, differentiation, proliferation, cell death, and metabolism [10], [11], [12].
miRNAs have been implicated in various biological processes including developmental timing, patterning and embryogenesis, differentiation and organogenesis, immune response, growth control and apoptosis.
They play important roles in many biological processes, including developmental timing, cancer, and aging.
C. intestinalis has been used for a wide range of biological studies including developmental and evolutionary studies.
Fortunately, much effort is taking place in the scientific community to optimize experimental designs at different levels of biological complexity, including (developmental) neurobehavioral studies.
Puf proteins have extensive structural conservation within their RNA binding domain and regulate a range of biological processes, including developmental patterning, stem cell control, and neuron function [ 3].
In Arabidopsis, miRNAs have been shown to play key roles in various biological processes, including developmental regulation, hormone response and stress adaptation [ 13- 17].
This unique versatility enables multiple plant biological processes to be controlled, including developmental programs and stress responses.
