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The early pharmacologists, physiologists and biophysicists were able to extract deep insights into biological processes with simple experiments and clear thinking.
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Of course, a mathematical model must simplify the complexity of the real world.The basic question is, can we capture the essence of biological process with our simpler model?
"Combining complex biological processes with very sophisticated informatics.
Enrichment of GO biological processes with FDR correction was used.
In general, ACF percentage was a better trait for QTL mapping in our study probably because it is a marker of a specific biological process with a more simple genetic architecture (i.e. smaller number of loci with larger effects).
Our work is easier to ethically justify and provides much needed demonstrations of biological processes in a simple, measurable system.
We ran a similar experiment: for each setup we computed the correlation between each of the three classifiers' AUC scores across GO terms in the biological process subontology with a simple classifier that predicts each GO term with a confidence given by the corresponding gene's degree.
The aspect of genetics that captivated Michael was the notion of examining complicated biological processes by doing relatively simple experiments, namely, genetic crosses.
e, GO biological processes associated with H3K27me3 regions that are morphogen dependent.
Biological processes associated with the 12 characteristic metabolites.
Vagad has many enriched biological processes compared with RAHS-14.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com