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Furthermore, IEC Hdac1- and Hdac2-dependent common and specific biological processes were identified, including oxidation-reduction, inflammatory responses, and lipid-related metabolic processes, as well as canonical pathways and upstream regulators related to environment-dependent signaling through steroid receptor pathways, among others.
Several biological processes were identified which may contribute to enhanced disease aggressiveness in African-American patients, including angiogenesis and chemotaxis.
Significantly (p < 0.05) affected biological processes were identified (Table 2).
A total of 664 overrepresented GO terms (p < 0.05) associated with biological processes were identified.
Potential roles of differentially expressed genes in some specific biological processes were identified.
However, genes related to other complex biological processes were identified in our study.
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While many components involved in these biological processes are identified, how components organize differently in health and disease remains unclear.
The advent of siRNA-based screens has revolutionized the efficiency by which functional components of biological processes are identified.
In general, a richer spectrum of biological processes was identified among the up-regulated genes compared with the down-regulated genes.
However, significant enrichment of biological processes was identified in Clusters 2, 3 and 4. Cluster 2 shared categories in common with Clusters 3 and 4; the most significant process in Cluster 2 was the NF-κB cascade (p-value 10-6).
Enrichments in the GO categories of Biological Process were identified.
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biological replicates were identified
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