Owing to the apparent involvement of σ receptors in a variety of biological processes, and the potential applications of σ ligands in pharmacology and medicine, interest in these receptors and their ligands has remained high, and there is a continuing search for new selective ligands that can serve either as agonists or antagonists at those biological processes that are mediated by σ receptors.
In summary, Dia proteins control diverse fundamental biological processes that are mediated by combinatorial interactions with different binding partners.
Calcium is an important intracellular messenger that mediates many biological processes that are relevant to the malignant process.
These multifaceted interactions underlie BAG3 ability to modulate major biological processes, that is, apoptosis, development, cytoskeleton organization and autophagy, thereby mediating cell adaptive responses to stressful stimuli.
Overall, these analyses emphasize the limited amount of functional information that we know regarding the biological processes that most of the TFs mediate, even for model plants such as Arabidopsis.
At the same time, a large number of analysed TFs could not be classified into any GO category, indicating the limited amount of functional information that we know regarding the biological processes that most of the TFs mediate, even for model plants such as Arabidopsis.
The complex biological processes that control cellular function are mediated by intricate networks of molecular interactions.
Paracrine transfer of chemical factors between two interacting cells is a fundamental biological signaling process that can mediate cell differentiation, proliferation or even cell death.
