miRNAs have been widely shown to modulate various critical biological processes, including differentiation, apoptosis, proliferation, the immune response, and the maintenance of cell and tissue identity1,2.
MicroRNAs (miRNAs) represent a class of regulatory small RNAs that play a role in a large number of biological processes including differentiation and organ development [14].
Therefore, SPARC is thought to influence several biological processes, including differentiation, migration, and proliferation.
PRC2 places H3K27 trimethylation marks and is involved in various biological processes including differentiation, proliferation, and stem cell plasticity 29.
It has been demonstrated that miRNAs have a significant role in various biological processes, including differentiation and development, metabolism, regulation of cell proliferation and apoptosis (Inui et al, 2010).
3, 5 Thus, a single miRNA might affect the expression of several mRNA targets, even within the same signaling pathway, and simultaneously control diverse biological processes, including differentiation, proliferation, migration, or cell survival.
MicroRNAs demonstrate an uncovered class of small and endogenous non-coding RNAs and play an important role in the normal biological processes, including cell differentiation, proliferation and apoptosis.
Histone deacetylases (HDACs) catalyze the hydrolysis of acetylated lysine side chains in histone and non-histone proteins, and play a critical role in the regulation of many biological processes, including cell differentiation, proliferation, senescence, and apoptosis.
miRNAs likely regulate diverse biological processes, including tissue differentiation and maintenance, and have contributing roles in varied disease processes, including cancer [2], [3], [4].
Many reports show that miRNAs play key roles in various biological processes, including cell differentiation, proliferation, apoptosis, stress resistance, fat metabolism, tumorigenesis, and tumor metastasis [7], [8], [9].
MicroRNAs (miRNAs) participate in crucial biological processes, including development, differentiation, apoptosis, and proliferation [4], [5] through imperfect pairing with target messenger RNAs (mRNAs) of protein-coding genes and transcriptional or post-transcriptional regulation of their expression [6], [7].
