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The Damaged DNA binding protein 2 (DDB2), is involved in nucleotide excision repair as well as in other biological processes in normal cells, including transcription and cell cycle regulation.
ROS act as a secondary messenger in cell signaling and are essential for various biological processes in normal cells.
EMT is increasingly recognized as one of the most important developmental biological processes in normal wound healing.
Thus, down-regulated genes in GBM exoRNA could either be caused by altered biological processes in normal cells as a response to or consequence of the disease, or by large numbers of tumour microvesicles with low levels of particular RNAs.
Given the contextual nature of E2F1's influence on various biological processes in normal and cancer cells we have to exercise caution in severing the arms of the E2F1 dragon so that it can be tamed in a way so as to restore its activities associated with death or senescence of cancer cells without activating other pathways involved in oncogenesis.
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EMT has been shown to play a role in organogenesis during embryonic development and is an important biological process in normal wound healing [ 2].
The modelling of iron homeostasis in relation to the main features of metabolism, energy production and oxidative stress may provide new clues to the ways in which changes in biological processes in a normal cell lead to disease.
Nevertheless, the correlation between 25 target genes and p63 status in an in vivo setting further supports our findings that these target genes contribute to p63-mediated biological processes in both normal and tumorigenic settings.
Biological networks representing either the normal biological processes in a specific "normal" cell type, or the modified processes in the tumor cells of a specific patient are assembled from computer "objects" representing the elements (genes, transcripts, proteins and protein modification states, complexes, metabolites, etc).
Nor are activists able to demonstrate health impacts as so-called "endocrine disrupters," i.e., hormonally active chemicals that can disrupt normal biological processes in the human body and result in adverse health effects.
As an adaptive response to hypoxic stress, hypoxic tumor cells activate several survival pathways to carry out their essential biological processes in different ways compared with normal cells.
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