Major biological process groups included genes related to cellular metabolic processes (30 %), primary metabolism (34 %), biosynthetic processes (19.81 %), regulation of biological processes (14 %), establishment of localization (18 %) and response to stress (1.5 %).
Surgical resection is today the basis for curative therapy, but a detailed understanding of the biological processes that regulate the establishment and progression of a malignant tumour may lead to improvements in non-surgical antitumour therapy.
Over the past decade, research effort on metastatic disease has been focused on the biological processes that influence the establishment of metastases.
Histone methylation is very important for the chromatin modification and regulation of gene expression [ 1– 4], which plays a crucial role in the animal development and a number of other biological processes, such as heterochromatin establishment, transcription regulation, parental imprinting, and cell fate destination.
Biological processes ontology for significantly regulated proteins.
For biological process ontology for L5D6 vs PP, the dominant GO items of the up-regulated transcripts included establishment of localization, localization and post-embryonic development, while the dominant GO items of the down-regulated transcripts included cellular component biogenesis, cellular component organization, cellular process and pigmentation.
Proteins that contain PDZ domains participate in a variety of biological processes, including signal transduction and establishment of epithelial apical-basal polarity.
Statistical analysis for enrichment for biological processes resulted in 1195 biological process GO terms being identified.
