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Because of the very interesting biological processes controlled by the daf-2 – daf-16 pathway, considerable effort has been made to identify the downstream targets of the pathway [5], [6], [7], [8], [9], [10], [11], [12].
Our results show that lipofuscin and apoptosis are markers of different age-dependent biological processes controlled by different genetic mechanisms.
These biological processes controlled by miRNAs in the miR-34 family are related to ENU cytotoxicity, genotoxicity, and carcinogenicity.
Finally, the consequences of these fluctuations in organelle abundance on the fundamental cell biological processes controlled by these organelles, ranging from secretion to metabolism, remain to be explored.
Overall functional categories (OFCs) provided an overview of biological processes controlled by RNA motifs by taxonomy and also according to RNA motif family.
Additionally, evaluation of alterations in MSC morphology provides valuable information that reflects complex biological processes controlled by the interactions between the cytoskeleton and the extracellular environment [ 18].
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Thus, aging is, indeed, a complex biological process controlled by multiple genetic, epigenetic and environmental factors.
However, in other cases, the abundance of some subgraphs may be attributed to adaptive optimization of the biological process controlled by the network, if the subgraph's connection pattern confers an advantage to the organism [ 27, 60, 61].
In order to infer possible molecular and/or biological processes controlled commonly by EDM2 and WNK8 or exclusively by each of these two regulators individually we used the "AmiGO" program http://amigo.geneontology.org/cgi-bin/amigo/term_enrichment to identify overrepresented Gene Ontology (GO) terms in gene sets 7 - 12 (defined in Table 1).
RNA-seq analysis revealed that the clubroot resistance conferred by Rcr1 involves complex mechanisms via a variety of biological processes controlled likely by corresponding transcription factors (TFs).
Multiple processes, including gene expression, X-chromosome inactivation, imprinting, chromatin organization and other biological processes are controlled by DNA methylation [ 4].
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