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Particular emphasis is placed on the role of estrogen in signaling pathway activation by mechanical stimuli, and on computer simulation in combination with cell biology to unravel biological processes contributing to bone strength.
In contrast to arguments advocating gene therapy, these studies suggest that the most likely successful drug therapy will have a wide therapeutic range, targeting as many of the components or biological processes contributing to restenosis as possible.
Our findings of distinct inflammatory patterns associated with airway thickening and parenchymal emphysema supports the existence of unique biological processes contributing to the syndrome of COPD.
This indicates that many of the biological processes contributing to GC resistance in ALL may be independent of lineage.
Long intergenic noncoding RNAs are key regulators of chromatin states for important biological processes, contributing to the development and progression of diverse diseases [ 56].
Complex-trait genetic association studies aim to identify robust associations between genotype and phenotype in order to enhance our understanding of the underlying biological processes contributing to the trait of interest.
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The mechanistic role of Notch in CSCs can be potentially explained by its ability to induce an epithelial-mesenchymal transition (EMT), a known biological process contributing to the development of CSCs [ 10].
This interdisciplinary approach permits integration of biological mechanisms and models of processes contributing to disease progression at various scales into mathematical models.
Social-economic factors are considered as the key to understand processes contributing to biological invasions.
Beyond gaining a basic understanding of the amino acid control of biological mechanisms, the characterization of how these processes contribute to the occurence of various diseases represents an important field of investigation in molecular nutrition.
While the same biological processes may contribute to tumor phenotypes in different cancers, the process by which this happens may be entirely different given the particular cellular context, tissue-specific gene expression and epigenetic influences.
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