Moreover, a total of 33 different pathways were identified with more than 3 genes affiliated, some of which were consistent with biological processes characterized by GO analyses.
Metastasis is a complex, multi-step biological process characterized by distinct, interrelated steps that vary in their timing and efficiency [ 1, 2].
The prevailing hypothesis concerning the biological importance of tumor budding is that it represents an epithelial-mesenchymal transition, a biological process characterized by increased migratory capacity and invasiveness [ 25].
Aging is an inevitable biological process characterized by progressive functional decline of all organ systems with simultaneous increase in oxidative damage as a result of reactive oxygen species (ROS) accumulation.
Many of the physical and biological processes that characterize arctic ecosystems are unique to high latitudes, and their sensitivities to climate change are poorly understood.
Motivation: Analyzing data from multi-platform genomics experiments combined with patients' clinical outcomes helps us understand the complex biological processes that characterize a disease, as well as how these processes relate to the development of the disease.
Genome-wide profiling of breast cancer tumors and cell lines are continually used to identify dysregulated biological processes that characterize the etiology and progression of the disease at the molecular level.
Employing a systems biology approach, we have identified for the first time the transcriptional profiles and corresponding biological processes that characterize the scope of ARI symptoms amongst four clinically distinct groups.
A summary of the results from this study showing the genes, pathways and biological processes that characterize the key molecular events in clinically prion infected mouse brain is provided as a schematic in Figure 7. Microarray experiments have been performed on tissues affected by many diverse diseases in efforts to document the changes in tissues at the transcriptional level.
The ability to understand complex biological processes by characterizing the activity of the molecular machinery governing processes such as DNA replication, transcription, transposition, recombination, protein synthesis, protein degradation and RNA processing, have greatly advanced our understanding of the living cell.
