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Finally, microRNAs (or miRNAs) are a class of small non-coding RNA species with critical functions across various biological processes by regulating gene expression.
They play an important role in biological processes by regulating gene expression at the posttranscriptional level [ 1, 2].
They play important roles in multiple biological processes by regulating genes that control developmental timing, growth, stem cell division and apoptosis [ 6- 9].
MicroRNAs (miRs) are ∼22-nucleotide noncoding RNAs that have key roles in fundamental biological processes by regulating the levels of multiple proteins.
Database URL: http://mtibase.sysu.edu.cn MicroRNAs (miRNAs) are ∼22-nucleotide (nt) endogenous RNAs that participate in important biological processes by regulating gene expression (1).
MicroRNAs (miRNAs) are small non-coding RNAs that have an impact on a wide range of biological processes by regulating gene expression at post-transcriptional level or protein systhesis level.
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Gene function can be assigned to a biological process by regulating gene expression.
Insulin plays a starring role in this fundamental biological process, by regulating the movement of glucose out of the blood and into cells.[2] Scientists now believe that insulin uses chromium as an assistant (technically, a cofactor) to "unlock the door" to the cell membrane, thus allowing glucose to enter the cell.
Genes and proteins function cooperatively and thus regulate common biological processes by co-regulating each other [ 13]; however, genes identified via the classical approaches are usually not functionally related and therefore may not reveal key biological processes.
It was reported that miRNAs regulate at least 10% of Caenorhabditis elegans genes through conserved interactions and a number of nematode miRNAs regulate biological processes by targeting functionally related genes [6].
So the VLDLR appears to regulate biological processes by binding or internalization of ligands, or by transducing extracellular signals across the cell membrane.
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