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This paper introduces a novel simulation methodology, SMIDGen, which better reflects both biological processes and systematic practice than previous simulation techniques.
First, we provide a new experimental methodology, SMIDGen (available from the first author), for generating simulated multi-marker datasets, and we show that SMIDGen can be used to evaluate supertree and combined analysis methods under a range of conditions that reflect both biological processes and systematic practice.
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To address this problem, we developed a systematic methodology for calibrating quantitative models of dynamic biological processes and illustrate its utility by validating a model of TRAIL (Tumor necrosis factor Related Apoptosis-Inducing Ligand)-inducellcell death.
We performed a systematic analysis for enrichment of genes belonging to defined biological processes and cellular pathways using the PANTHER classification system [ 11].
Systematic functional genetics/genomics is powerful in the identification of genetic components of biological processes and their interactions.
Enriched biological processes and molecular functions using Gene Ontology database.
Systematic characterization and co-expression analysis of OsWD40 genes enable us to understand the networks of the WD40 proteins and their biological processes and gene functions in rice.
(Biological processes and Molecular functions).
The top 3 biological processes were metabolic processes, regulation of biological processes, and response to stimulus.
Enrichment of biological processes and pathways.
It is anticipated that this approach will allow systematic analyses of inductive, homeostatic and pathologic signaling inputs, and thereby allow more precise definition of mechanisms underlying biological processes and phenotypes than is possible with existing approaches.
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