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The identified biological processes and signalling pathways collectively targeted by co-expressed miRNAs in CRC provide a basis for understanding the functional role of miRNAs in cancer.
Our aim is to identify genetic interactions for CLN3 with a view to placing it within a gene regulatory network and to identify the cell biological processes and signalling pathways that require, or impinge upon, CLN3 function.
In turn, they identified putative biological processes and signalling pathways that are significantly present in those gene lists.
Several biological processes and signalling pathways were shown to be at the centre of BaP-modulation, as described below.
As part of the Cancer Drug Discovery and Development series, this book aims to explain basic biological processes and signalling pathways and to link that knowledge to the anticancer drugs associated with those pathways.
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Bioinformatics analysis implies the biological processes and signaling pathways mediated by candidate lncRNAs involved in the control of GO toxicity.
Protein protein interactions (PPIs) are central to our understanding of protein function, biological processes and signaling pathways.
Extensive bioinformatics analysis revealed that these proteins are involved in biological processes and signaling pathways that are associated with the development of recurrent AO.
Exposure to 1.4 and 11 Gy also affected biological processes and signaling pathways involved in cell cycle regulation and proliferation (1.4 Gy: small GTPase signal transduction and transmembrane receptor protein tyrosine kinase signaling pathway; 11 Gy: G protein signaling and G protein receptor protein signaling pathway).
The selected genes would also allow us to deepen into the overrepresented biological processes and signaling pathways common to glucose uptake in different metastatic tumors, as well as into the potential protein-protein interaction (PPI) subnetworks found among the selected features.
GO and KEGG pathway analysis also revealed several functionally involved biological processes and signaling pathways.
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