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The long term goal of this research is to develop a probabilistic language to specify which proteins might be active in a given biological process based on the type of interacting partners they have, protein motifs, or transcriptional profiles.
Up-regulated and down-regulated genes for the GO system biological process based on EASE are shown in Tables 2 and 3, respectively.
Thus a subsystem is an assembly of molecular functions that perform the same biological process, based on new controlled vocabularies and functional relationships.
Feature selection to aid in understanding a biological process based on gene expression data is most useful when a maximally-sized subset of informative genes can be presented to the researcher.
In contrast, Calcium signalling was identified as one of the predominant KEGG pathways activated at 21 DPP (Additional file 3: Table S3) and the regulation of calcium was identified as a significantly enriched biological process based on gene ontology analysis (Additional file 4: Table S4).
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Mathematical models for biological processes based on ordinary and partial differential equations.
It is rooted in the investigation of biological processes based on the study of molecules and their interactions in the context of cells and tissues, and in understanding how the vast information context of the genome orchestrates the behavior of the cell.
Thus, both genes with and without known assigned functions can be linked to specific biological processes based on their promoter similarities and their predicted co-expression (under specific conditions) with genes of well-defined functions.
The gene ontology analysis could categorize the 1301 up/down-regulated genes (>2 fold up/down-regulation, P<0.01) into various biological processes based on their known roles or functions.
Mathematical modeling provides several ways to describe biological processes based on experimental information of different kind.
Kalfalah and colleagues reported on 117 age-related biological processes based on the transcriptome data (Tab. S9) [ 10].
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