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Here we provide a rationale for this observation by studying the prognostic power and the underlying biological pathways of different gene signatures.
Recent research has suggested possible differential biological pathways of different progestins used in contraception that may have a role in increasing susceptibility to HIV acquisition (Tomasicchio et al., 2013).
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Using content analysis, the identified clusters were then qualitatively grouped into five different biological pathways of degeneration that appear to have face validity.
Biological pathways of DB sites H3K27ac were analyzed using ReactomePA and the Reactome Pathway Knowledgebase64,65.
Canonical pathway analysis identified the biological pathways of most significance.
Systematic characterization of expression changes in biological pathways among different types of cancer will eventually lead to a better understanding of which perturbations in the cell give rise to cancer.
Different effects of PM and PNC might reflect different biological pathways activated by different particle properties.
As yet no study has examined the changes in gene expression that accompany development in children and correlated them with biological pathways at different ages and stages of development.
Although TFBS is a relatively limited technique for probing transcriptional regulatory networks, these data suggests that different compounds perturb a common set of biological pathways, but by different regulatory mechanisms.
Recently we developed a bioinformatic environment called Eu.Gene [22] containing a repository of all the freely available biological pathways and different statistical methods dedicated to analyze expression datasets and assess for enrichment in biological pathways.
Are degrees of controllability of the biological pathways different between normal and abnormal Cells?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com