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This is opposed to the commonly followed strategy in which the most significant SNPs from a genome-wide association analysis are annotated to search for possible biological pathways associated with the trait.
Therefore, the objective of this study was to use a genome-wide association approach to identify SNP markers, candidate genes and biological pathways associated with AMIR and CMIR.
"I think we will find out a bit more about the biological pathways associated with Sad.
This link provides the BioSystems identifiers (BSID) [35] for the biological pathways associated with a given assay in PubChem.
All differently expressed proteins were mapped onto the KEGG database to determine the altered biological pathways associated with these plasma proteins.
Set C had 265,470 compounds with 3-D description that were non-inactive against proteins involved in at least one of the 4,540 biological pathways associated with the biological assay considered.
Metabolomics is a promising tool in nutrition and health research where complex metabolite profiles reflect the metabolic effects of foods and diets as well as the biological pathways associated with diet-related diseases.
The majority of molecular genetic studies have been candidate-based, however genome-wide studies are emerging, with the potential to elucidate novel biological pathways associated with individual differences in morality.
In the present study, we proposed a gene coexpression analysis to investigate biological pathways associated with treatment response predisposition and their regulation by microRNAs (miRNAs) in peripheral blood samples of MDE and healthy control subjects.
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The above results indicated a specific pattern of miRNA expression and the biological pathway associated with leukemia relapse.
One solution to the problem is to choose gene predictors from biological pathways associated a priori with the phenotype or outcome of interest.
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