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The data contain 43,304 biological papers (including 3957 papers of biophysics), which account for 82.01% of the total.
Statistical power -which is primarily a function of noise in the data and sample size- is typically low in social, behavioural and biological papers [49], [50], [51], [52], [53], and relatively high in disciplines like physics, chemistry or geology.
Many biological papers (just during 2008, there are hundreds of biological papers published) support the epigenetic changes and the view that epigenetic changes are the driving force for cancer initiation, progression and metastasis, more important than gene mutations in cancer initiation and progression.
Acronyms, which are pervasive in biological papers, are also disambiguated (Okazaki et al., 2010) and normalized into identifiers if the disambiguated results belong to the semantic categories which KLEIO is able to deal with.
(There are a large number of biological papers documenting this. I have just listed a few of them in our paper. I can provide many more published papers from cancer journals if one wishes).
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Writing a biological paper before computers is one thing, but Ashmore remembered the problems of producing mathematical formulae in a typed manuscript, explaining that "you wrote the paper and probably took it along to somebody to be typed… And then it came back with spaces where you had to write in the equations".
DR and HC provided the technology platform (array production and laboratory procedures) and advice relating to it, KM conceived of and planned the experiment implemented in the biological paper, produced the extensive clone library used for the arrays, performed all hybridisations and arrays scans and drafted parts of this manuscript.
Indeed, there is a general feeling that the extremely high impact factors of multidisciplinary journals like Nature and Science are largely driven by the non-evolutionary and/or non-biological papers they publish [also see e.g. 7].
Instead of perpetuating the debate on the level of in principle-arguments, this paper aims first at reconstructing functional talk in the biological research papers of Marom and Braun, which focus on two different kinds of evolving networks, and in discussing the ontological consequences which the authors draw from their results.
Indeed, it was his quantitative understanding of the morphogenetic possibilities of Notch signaling that led him to produce, in 2003, what many regard as his best modeling paper, and what I consider one of the best biological modeling papers of all time [ 5].
About half of the authors responded, and after excluding replies that his programs could not decipher, Calcagno had a data set covering the prepublication history of 80,748 biological science papers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com