We found that the external magnetic fields can affect the biological outcome of magnetic nanoparticles.
Such a binding is usually of utmost importance for the biological outcome.
Therefore, for years several experimental designs have ignored the potential contribution of this molecule to the final biological outcome.
This aspect, referred to as region specificity, may be critical for the biological outcome of drug action.
In addition, it becomes clear that the function of the mitochondrial pathway is context-dependent and cell death is not necessarily always its "intended" biological outcome.
This is an ideal project that combines my colleagues' project-based engineering experience to identify problem sources with my basic biological research training in assessing the biological outcome.
The in vivo bioassay for GH (bioGH) provides a more physiologically relevant measurement than an in vitro immunoassay, since bioGH is quantified on a biological outcome.
Proteins that regulate mRNA metabolism are often bipartite: an RNA binding activity confers substrate specificity, and a "functional" domain elicits the biological outcome.
A novel ex-vivo experimental platform was developed to facilitate in-situ loading of rabbit functional spinal units (FSUs) with relevant biological outcome measures.
This study was designed to test the hypothesis that transcutaneous ultrasound (US) exposure may augment the transfection efficiency and biological outcome associated with nonviral DNA gene transfer.
However, indirect validation may be unavoidable in FEA because no concrete biological outcome can be directly attributed to most FEA studies of force distribution; thus, it is difficult to generate outcome data for comparison with experimental data.
