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Although we statistically adjusted for age, this was unlikely to fully account for the biological increase in some biomarkers as age and BMI naturally increase.
It may relate to a true biological increase, but the possibilities of technical factors (such as difference in tissue procurement [biopsy versus surgery]) have not been excluded.
Two mechanisms of action may be at work: first, a biological increase in susceptibility due to immunosuppression but also social discrimination that could drive a delay in accessing facility-based care.
The increase in Ki67 LI within the placebo groups a few weeks apart has been associated with the most highly proliferating molecular subtypes (triple-negative and HER2-positive BC; Tagliabue et al, 2003; Gandini et al, 2013), suggesting a true biological increase in proliferation rather than a technical artifact due to different tissue sampling.
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Although only a few trials aimed to study drug-free remission, there is some evidence that biologicals increase its likelihood; there might be differences between medications in this respect.
The rate of biodegradation and biological activity increases with the increase in temperature.
It's the fact that we've also seen him in these other areas, in chemicals, but also especially in biological weapons, increase his capacity to produce and deliver these weapons upon, upon his enemies.
This observation supports the possibility that biological processes increase the degree of perfection of genomic IRs.
As biological databases increase in size and complexity, the classical mechanism of data exchange, database duplication, can become impractical.
Consequently, as the numbers of institutions and personnel involved in biological control increase, the quality of recordkeeping decreases.
An early onset of disease probably reflects increased biological predisposition or increased susceptibility to specific environmental risk factors [57].
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