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This is also the first report where two dnd operons were found within a strain although the biological implication is unknown.
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A. With respect to the findings that H2BE receives dramatically reduced monomethylation at Lys5 compared to canonical H2B, we agree with the reviewers that the biological implication is presently unknown.
Nevertheless, evidence of significant biological implications is emerging [ 4].
Some FRs appear to be replaced by less-studied chemicals whose health implications are unknown.
Overall the evidence focuses on short-term benefit while the longer-term implications are unknown.
The biological implications are not discussed.
Whether this has any biological relevance is unknown.
For most of these proteins, however, biological function is unknown.
Exactly how this mutant mediates this biological effect is unknown.
The biological significance of these mutations is unknown.
The biological significance of this gene is unknown.
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