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As the coding sequence of the guinea pig (Gp) survivin gene as well as its biological functions were not known, we cloned the respective cDNA, revealing an open reading frame encoding for a protein of 142 amino acids.
These biological functions were not significantly activated in the mutant-infected brain; in contrast, many SDEG involved in the host protective responses were activated only in the mutant-infected mouse brain.
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Rat/mouse hemokinin 1 (r/m HK-1) is a novel tachykinin peptide whose biological functions are not fully understood.
Apelin, as the endogenous ligand of the APJ receptor, is a novel identified neuropeptide whose biological functions are not fully understood.
Although the contribution of each partner and domain of RanBP2 to its biological functions are not understood, physiological deficits of RanBP2 downregulate glucose catabolism and energy homeostasis and lead to delocalization of mitochondria components in photosensory neurons.
The caveat is that real biological functions are not random.
These results suggest a critical role for Olig1 in the repair of the adult CNS, however, its biological functions are not fully understood.
Moreover, biological functions are not, in general, realized by individual proteins, but, rather, by networks of intricate interactions between numerous genes.
Similar observations of species specific transcript sequences were observed in other transcriptomic studies and were attributed to the presence of novel sequences or transcripts of 5' and 3' untranslated regions or genes with homologs in other species whose biological functions are not yet assigned.
However, their endogenous ligands and biological functions are not clearly identified [ 23].
Important biological functions are not properly regulated during in vitro culture due to the two-dimensional nature of the culture.
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