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Synthetic biology is an emerging field of bioengineering that aims to design and implement novel biological functions in vivo.
Structural polymorphism is one of the important issues with regard to G-quadruplexes because the structural diversity may significantly affect their biological functions in vivo and their physical property in nano-material.
When dosed orally in mice at 50 mg/kg twice a day (BID), 48 showed an unbound maximal plasma concentration (Cmax) >15-fold over its cell EC50, thereby providing a robust chemical probe for studying KDM5 biological functions in vivo.
The antiviral activities of the new ISGs and their biological functions in vivo await further investigation.
Given the fact that RBP-J promotes certain components of canonical M1 as well as M2 responses, it is anticipated that RBP-J would possess complex and context-dependent biological functions in vivo that could not be attributed as simply promoting or suppressing inflammatory and immune responses.
Although Lrig1 and Lrig3 may share the ability to interact with a wide variety of binding partners in vitro, whether or not this reflects similar cell biological functions in vivo remains unclear.
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This surprising result demonstrates that the localisation of the viral IFNα/βBP at the cell surface is required to efficiently fulfil its biological function in vivo.
The two remaining genes, i.e., miR-1975 and miR-1979 were not further studied because there is, to our knowledge, not a single reference to their biological function in vivo.
It is concluded that the proper intracellular localization, directed by the N-terminal targeting and transmembrane motifs, is required for stability and subsequent proper biological function in vivo.
A normal biological function in vivo usually involves a series of phosphorylation processes [2].
In order to investigate the effect of PDGF release rate on PDGF biological function in vivo, nine groups of 3 animals each were prepared to test in a rat wound healing model.
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vital functions in vivo
biological functions in life
biological functions in vitro
biological functions in living
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biological membranes in vivo
biological profiles in vivo
biological tissues in vivo
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biological functions in cancer
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biological functions in epidermal
biological roles in vivo
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