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Since insects are unable to synthesize cholesterol de novo, an appealing way to explain this evolutionary acceleration is that ERGp orthologs have other biological functions in addition to sterol synthesis.
However, TIMPs exhibit several other biological functions in addition to the inhibition of active MMPs.
Carotenoids are ancient compounds, involved in a multitude of biological functions in addition to coloration (e.g., [ 34]).
As summarized in Table 1, antifungal defensins and defensin-like AMPs exhibit complex biological functions in addition to antimicrobial toxicity.
Phylogenetic analyses suggest that different BH3-only proteins may have acquired BH3 motifs by convergent evolution and may have biological functions in addition to apoptosis regulation.
WD40 repeats mediate protein-protein interactions and are involved in regulating numerous biological functions in addition to their role in actin nucleation [ 43, 44].
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The role and other biological function in addition antifungal toxicity is supposed at PAF.
Therefore, it is believed that ARD1 has diverse biological functions in mammalian cells, and that it acetylates various molecules in addition to HIF-1α and β-catenin.
In addition, peptides from laminin α1 support the biological functions in hepatocytes [ 35].
In addition, both metals were found to modulate genes that encode proteins with similar biological functions in the cell.
In addition, they can also specifically modify a subset of genes, thus suggesting that they could mediate both common and specific biological functions in invasive breast carcinomas.
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