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So far, a major focus has been placed on methods for identifying differentially expressed genes from RNA-seq data [ 16– 18] because such analysis methods that are simpler than, e.g., network-based approaches yet provide meaningful insights into the basic biological functioning of different physiological conditions.
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However, the biological function of different topographic materials utilized as bio-scaffolds in vivo have not been rigorously characterized.
These results suggested that the design of biomaterials based on the biological function of different material elements was an effective approach for bone tissue engineering applications.
The biological functions of different VEGF-A isoforms in pathological angiogenesis, such as tumor angiogenesis, are still unclear.
The inferred network could then be used to interpret the local, dynamic biological function of different phosphorylation sites as they undergo reversible covalent modifications.
The activities of VEGF189 in nuclear translocation [34] and crosstalk of VEGF-signaling pathways with integrins [39] may also affect the biological functions of different VEGF isoforms in tumor angiogenesis.
Despite our increasing understanding of the biochemical and cell biological functions of different co-chaperones, we know very little about how coordinated alterations of multiple components of the co-chaperone network could lead to dynamic adaptations of the proteostasis machinery.
We measured the biological function of different subsets of PD-1+ T cells and clinical impact in FL patients.
The analysis of PPIs is critical to understanding the biological functions of different proteins during cellular processes.
In order to study the biological function of different regions of the DAYSLEEPER coding sequence in vivo, complementation was attempted of daysleeper mutant plants with 3 different deletion versions of the DAYSLEEPER coding sequence.
In all the three organs analyzed, about 2/3 of the transcripts were identified as tissue specific, highlighting once again the strong link between the biological function of different tissues and gene expression.
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