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High-dimensional gene expression data provide a rich source of information because they capture the expression level of genes in dynamic states that reflect the biological functioning of a cell.
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Such functional analysis may help to elucidate the biological function of a miRNA implicated in the condition of interest.
Various functional modules are collected for a better understanding of the biological functions of a SNP combination (Table 1).
Theoretically, the labor- and time-intensive phase of functional screening could be replaced by computational tools that reliably predict the biological function of a microRNA in a certain transcriptomic environment.
Site-specific labeling is an important methodology to elucidate the biological function of a target protein.
The biological function of a short peptide is related to its three-dimensional structure within its interacting protein.
Some MeSH annotations (such as solvents, carcinogens, inhibitors, and so on) are too general to describe a specific biological function of a compound.
On the one hand, it is essential that we encourage free thinking and speculation about the biological function of a trait in relation to the organism's environment.
The molecular interaction and, hence, the biological function of a small molecule is related to its three-dimensional structure when interacting with the protein.
We report here the expression and biological functions of a previously uncharacterized rice gene that we have named NRR (nutrition response and root growth).
Still, the identification of potential protein binding pockets and occluded cavities remains a central issue, as the capability to interact with other proteins or small ligands determines the biological function of a protein.
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