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Perhaps the largest challenge to developing new therapeutics against these commonly altered pathways lies in understanding the biological functionality of these mutations.
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Moreover, immunohistochemistry results showed that cells seeded on the scaffold maintained their endothelial phenotype, demonstrating the biological functionality of the microfabricated GelMA scaffolds.
The main parameters affecting the scaffold performance concern morphology and architecture (e.g., pore shape, size, distribution, and interconnectivity), structural properties, and surface chemistry, the latter affecting cells adhesion and growth, and therefore the biological functionality of the graft.
The biological functionality of the protein-NP conjugate depends on the protein's ability to interact with target molecules, which is affected by NP characteristics such as size, curvature, aspect ratio, morphology, crystal structure, and surface chemistry.
It is widely accepted that most of the biological functionality of the cell arises from complex interactions between their molecular components that define operational interacting entities or modules [8].
It is widely accepted that most of the biological functionality of the cell arises from complex interactions among their molecular components that define operational interacting entities or modules [3].
The biological functionality of this hydrogel platform was evaluated for cartilage tissue engineering.
Most of the biological functionality of the cell arises from complex interactions between their molecular components that define operational interacting entities or modules [ 5].
It is widely accepted that most of the biological functionality of the cell arises from complex interactions between their molecular components that define functional entities or modules that operate as small subcellular systems [ 3].
Reaction conditions are typically mild and help to preserve the biological functionality of the protein target; it can occur rapidly with high specificity; and it generally gives a high yield.
To improve the biological functionality of the RLP, our group has produced multiple constructs that incorporate cell adhesion domains (RGD), enzymatic degradation domains (MMP-sensitive), and heparin-binding domains (HBD) to yield a multibiofunctional material.
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