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The biological functionality of genes in the two datasets was assessed using Gene Ontology [ 32] classifications.
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In addition, in problems of such large input dimensionality (5000 or more on microarray chips), and relative sparsity of patient examples (a few hundred is typical), it is statistically plausible to select small subsets which are randomly correlated with any given desired outcome, irrespective of any biological functionality of the gene expression itself.
The results of this study provide comprehensive knowledge on global gene expression, and biological functionalities of differentially expressed genes in chicken embryo lung cells in response to ILTV infections.
The biological functionality of this hydrogel platform was evaluated for cartilage tissue engineering.
To date, little is known on the biological functionality of SPATS2L.
This is essential for numerous biological problems, such as the analysis of genes contributing to certain diseases, assigning biological functionalities to genes or when the conditions of a microarray are diverse [ 12].
Comprehensive knowledge of gene expression and biological functionalities of host factors during vaccine ILTV infection can provide insight into host cellular defense mechanisms compared to those of virulent ILTV.
A KEGG pathway enrichment analysis was used to assess shared biological functionality amongst genes with either overlapping or independent eQTL.
Regional genomic properties are therefore relevant to the functionality of genes.
The assigned functionality of genes covers a broad range of GO categories.
Again, this multi-functionality of genes may help to rethink what genetic and biological determination means (see also the discussion of biological determinism in the entry on feminist philosophy of biology).
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