These results suggest two mechanisms: (1) the analysis is robust and indicated the same biological functionalities for all experiments despite the experimental differences, and (2) the meta-analysis adds new genes and data to the already existing data, but does indicate new biological mechanisms for the reaction of chicken hosts to the Salmonella infection.
MNPs should possess precisely tunable magnetic properties and biological functionalities for early diagnosis and efficient therapeutics, which could be achieved by tailoring the MNP size, shape, composition, and surface coating during chemical engineering processes.
Recently, new bioinformatics tools have been developed to facilitate efficient analysis of biological functionalities for large numbers of differentially expressed genes obtained from microarray analysis.
Finally, the method for incorporating biological functionality into the material should be applicable to a broad array of bioactive molecules, from small molecules to peptides to proteins.
Boolean logic function IAND corresponds to the biological functionality where the absence of a gene/protein is required for the activity of another gene/protein.
Critical for many of the applications for such materials is incorporating polymers with a given optical, electronic, or biological functionality into the nanostructured material.
The prime feature of a sequence and its biological functionality is the structure.
The lists of differentially expressed genes were analyzed for biological functionalities using the DAVID (The Database for Annotation, Visualization and Integrated Discovery) software [ 34- 36], version 6.6.
The biological functionality of genes in the two datasets was assessed using Gene Ontology [ 32] classifications.
This intriguingly broad variation provides an excellent model for studying biological functionality and morphological evolution using the modern tools of molecular evolutionary biology and comparative genomics [ 3, 4].
