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RNA-seq analysis provides a powerful tool for revealing relationships between gene expression level and biological function of proteins.
Because the physical model in the fit affects the characteristic unfolding time, these results have important implications on our understanding of the biological function of proteins.
We focus here on the impact of using RNAi to probe the biological function of proteins for target identification and selection for discovering small molecule drugs.
Recent advances in methodology and data analysis are helping HXMS deliver on its potential to uncover the connection between conformation, dynamics and the biological function of proteins and complexes.
The biological function of proteins requires the ability to change conformation [17].
Identification of the glycation sites in protein may provide guidelines to understand the biological function of proteins glycation.
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This situation happens for clusters which are mainly composed of genes related with the biological function of protein synthesis and protein degradation as indicated in Figure 12.
The identification of glycation sites in protein may provide guidelines to understand the biological function of protein glycation.
These keywords have been used in many studies to automatically annotate proteins or assess the biological function of protein clusters (e.g. [ 31, 32]).
Amongst others, we found that the heat tolerance genes have a predicted biological function of protein folding and biosynthesis, cell wall modification, and calcium signalling.
Folding and unfolding are fundamental biological processes in cell and are important for the biological functions of proteins.
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