Such functional analysis may help to elucidate the biological function of a miRNA implicated in the condition of interest.
Theoretically, the labor- and time-intensive phase of functional screening could be replaced by computational tools that reliably predict the biological function of a microRNA in a certain transcriptomic environment.
Site-specific labeling is an important methodology to elucidate the biological function of a target protein.
The biological function of a short peptide is related to its three-dimensional structure within its interacting protein.
On the one hand, it is essential that we encourage free thinking and speculation about the biological function of a trait in relation to the organism's environment.
The molecular interaction and, hence, the biological function of a small molecule is related to its three-dimensional structure when interacting with the protein.
Some MeSH annotations (such as solvents, carcinogens, inhibitors, and so on) are too general to describe a specific biological function of a compound.
Still, the identification of potential protein binding pockets and occluded cavities remains a central issue, as the capability to interact with other proteins or small ligands determines the biological function of a protein.
The biological function of a single islet inside a microfluidic device has been examined for intracellular Ca2+ [75] 75], amino acids [78], cellular impedance [77], or insulin secretion [74, 76] under dynamic external stimuli.
However, there are a large number of complex diseases such as cancer that cannot be effectively treated or cured only with one medicine to modulate the biological function of a single target.
Our results can be useful to understand the relationship between the operon structure and the biological function of a gene network, and also may help in synthetic biology design.
