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The activity of this receptor remains a key factor in the development and administration of glycoprotein pharmaceuticals, yet its biological function has remained elusive.
While other TRAFs have been mostly implicated in the immune system as adaptor proteins of TNF-R and IL-R [4], [5], the TRAF4 biological function has remained elusive [6].
This pigment was described in 1967 (26), but its biological function has remained unknown.
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Liver function has remained normal throughout.
The engineering of synthetic biological systems to perform programmed information processing and computational functions has remained a challenge.
So far no general biological function has been found, and many of the functions assigned to S-layers still remain hypothetical.
Recent studies suggest that Pf332 assembles together with a number of different surface-related proteins such as the RIFINs and PfEMP1 in the erythrocyte-cytoplasm to be directed together to the erythrocyte membrane [18] although the biological function of Pf332 has remained unclear.
Dnmt2 mutant mice, flies, and plants were reported to be viable and fertile, and the biological function of Dnmt2 has remained elusive.
The primary biological function of the endogenous cellular prion protein has remained unclear.
Since it was first described in 1981 (Bast et al, 1981, 1983), the biological function of ovarian cancer tumour antigen CA125/MUC16 has remained mostly unknown.
Finally, evidence for a dependence of Ras on Rac1 for biological functions accompanied by evidence of Ras-induced Rac1 activation in vivo has remained elusive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com