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Importantly, these methods allow us to detect potential posttranslational modification of the mKIAA/KIAA proteins and to predict their biological function based on their subcellular localization.
It is widely known that some proteins gain biological function based on their site of expression.
Numerous genes were categorized by biological function based on published studies (see Materials and Methods), including cell adhesion (Table 3).
This variation suggests distinct signaling and regulatory mechanisms for each GOG, consistent with their presumed general biological function based on established classification [ 22].
The z-score algorithm in IPA predicts the activation status of a biological function based on the direction and pattern of expression of member genes.
Identified poplar proteins were assigned putative biological function based on Gene Ontology Annotation [ 120] of their most similar proteins from other species or based on literature.
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► Additional biological functions based on their signalling activity are highlighted.
DETF cluster membership and associated biological functions based on the information of GeneOntology.
However, limited access to tissues of these animals has precluded detailed analyses of biological functions based on gene expression.
The activation z-score is used to infer likely activation states of biological functions based on comparison with a model that assigns random regulation directions.
We showed that gene modules generated by SSIM gave higher specificity with stronger association with biological functions based on the assessment of GO and MIPS annotation terms.
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