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We identified cell adhesion as a biological function associated with prostate tumorigenesis.
Gene ontology analysis (Table 3) identified Cancer as the top biological function associated with this gene set, with 130 of the 527 targets linked to Cancer through GO terms (p-value range 5.86E−05 to 2.87E−02).
Another interesting biological function associated with the miRNA gene targets is steroid hormone metabolism.
These proteins do not have any biological function associated with DNA replication, initiation, and elongation and it is probably safe to assume that they constitute false positive predictions added in the predicted HeLa complex to the manually verified CORUM complex.
There is no apparent biological function associated with C4d alone [ 4], but due to its covalent binding and relatively long half-life, it can be considered as an activation marker of the classical and lectin pathways of complement.
Two-hundred and sixty-five genes were identified as being highly expressed (FDR = 0%) in claudin-low, CNS and melanoma cell lines; Ingenuity Systems Pathway Analysis found that "cellular movement" was the top biological function associated with these genes (Supplemental Fig. 4).
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To analyze the seminal plasma proteome and biological functions associated with sperm functional alterations.
Biological functions associated with these focus genes were identified using the Functional Analysis using the Ingenuity Pathways Knowledge Base.
Of course, it's perfectly possible that statins can improve some biological functions associated with aging and worsen others.
To gain further insight into the biological functions associated with Nampt mediated pathogenesis of CIA, we submitted the 690 DEG for pathway analysis.
We then used ontology software to define the biological functions associated with these clusters.
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