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Bio-sensing represents one of the most attractive applications of carbon material based electronic devices; nevertheless, the complete integration of bioactive transducing elements still represents a major challenge, particularly in terms of preserving biological function and specificity while maintaining the sensor's electronic performance.
It has a similar structure to CTLA-4 but different biological function and specificity for ligands.
However, a more complete understanding of the biological function and specificity of the diverse HDAC isoforms and their involvement in the cancer process is necessary.
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Members of the annexins family are believed to be involved in a wide range of biological functions and the specificity of these functions can presumably be determined by proper targeting to the correct membrane or membrane domain.
In addition, glycopolymers have also been shown to interact with lectins, mimic biological functions, and offer specificity in delivery.
Due to their biological function and high level of target specificity, these enzymes are under intense investigation as tools for gene targeting.
However, the precise biological functions and substrate specificities of these kinases have not yet been defined.
With a growing set of reference signatures, it will be possible to define the degree of specificity of individual genes for a defined biological function and to develop signature based functional annotation tools.
Top probe sets were selected based on probe set specificity, strength of association to the Comt locus, biological function, and expression pattern for each relevant brain region in the AIBS (www.brain-map.org).
The biological function and substrates of STK35 are not known.
The selection was mainly based on gene ontology data about biological functions and disease relatedness of the proteins as well as the availability and specificity of antibodies commercially available.
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