In addition to providing detailed insight into the structure and organization of the CVS and MBC methylomes in the context of promoters, CpG islands and gene bodies, we present novel findings relating the methylation levels of these genetic elements to gene expression levels, biological function and primary DNA sequence.
The objective of this study is to empirically examine the relationship between biological function and the rate of sequence divergence after a duplication event.
Contact: [email protected] or [email protected] Calmodulin (CaM) is an intracellular calcium sensor protein that interacts with a large number of proteins to regulate their biological functions and exhibits sequence conservation across all eukaryotes (Bouche et al., 2005).
One subclass consists of those RNAs that require distinctive secondary structure motifs to exert their biological function and hence exhibit distinctive patterns of sequence conservation characteristic for positive selection on RNA secondary structure.
The potential biological function and sequence/structure conservation of the multibranch structure identified in this work makes this region a new attractive therapeutic target.
To refer to a particular vocabulary describing knowledge associated with a patchwork of biological data, objects, sequences, biological functions and functionalities and other general features of biological processes.
We describe a set of rules for naming chromosomes and identifying loci, genes, and alleles based on biological function, mutant phenotype, and sequence identity, and suggest ways of dealing with aliases (synonyms), sequence variants, and loci identified by multiple annotations of the genome assemblies available from various sources.
But 67.2% of them are hypothetical proteins or orphan sequences, their real biological functions and medical significance require further investigations.
These signatures are used for the classification and automatic annotation of protein sequences by assigning biological functions and gene ontology (GO) terms.
Summary: A motif is a short DNA or protein sequence that contributes to the biological function of the sequence in which it resides.
Exploring the sequence characteristics of sRNAs described in this study showed that sRNAs predicted to have similar biological function share common sequence motif.
