A biological expression system using genetic techniques based on a fusion technology would be a more efficient method for the production of bioactive peptides (Kim et al. 2006; Renye and Somkuti 2007).
Baculoviruses have been used extensively in many biological applications such as protein expression systems, as models of genetic regulatory networks and genome evolution, as putative non-human viral vectors for gene delivery, and as biological control agents against insect pests [ 7- 11].
Baculoviruses have been used extensively in many biological applications, for example as protein expression systems, as models of genetic regulatory networks and genome evolution, as putative nonhuman viral vectors for gene delivery, and as biological control agents against insect pests [ 4- 6].
As mentioned, contemporary immunology has established its fundamental theory as a biological expression of personal identity, wherein the 'immune self' is defended by the immune system.
A slight modification was that the nontoxic tetanus toxin fragment C (TETC) was inserted to the L. lactis expression system as a biological adjuvant.
In a biological system, expression levels of groups of genes may correlate with each other for various reasons such as co-regulation.
The choice of an appropriate expression system remains empirical, largely depending on the biochemical and biological properties of the target proteins (Bernaudat et al., 2011).
They made use of a prokaryotic expression system to produce p.N103K leptin and demonstrated that the p.N103K mutation drastically reduces the biological activity of the protein [19].
While heterologous over-expression systems have allowed identification of several of the potential biological roles of this receptor, its precise function remains largely elusive.
In real biological systems, protein expression does not correlate with gene expression, especially at steady state, due to different translation and degradation rates (Belle et al., 2006).
