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The DuoGel™s were evaluated based upon quantitative physicochemical and biological evaluations defined by a Target Product Profile (TPP) acceptable for vaginal and rectal application.
Fig. 3 The biological evaluations.
L929 cells were used for biological evaluations.
More detailed biological evaluations of selected compounds are also presented.
Preliminary biological evaluations revealed that most of the compounds exhibit insecticidal activity against N. lugens.
HW and YZ assisted in the biological evaluations of the NPs.
HZ and LX assisted in the biological evaluations of the NPs.
Based on primary screening, two compounds (5 and 11) were subjected to further biological evaluations.
Biological evaluations demonstrate that multiple structural features control the biological potency.
Dasatinib was utilized as positive control to validate in both biological evaluations.
The chemical synthesis of four candidates allowed extensive biological evaluations for their anticancer activity.
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